For example, NextJorunal is using it for React SSR [1]. There are other companies using GraalVM's JS engine for similar functionality.

The Dutch Police is using GraalVM's interop between Scala and R for their data science [2].

I'm sure there are other projects which explore the benefits of having a polyglot runtime, would love to hear about those efforts.

[1] https://nextjournal.com/kommen/react-server-side-rendering-w... [2] https://vimeo.com/360837119