https://rawlsmd.com/health-articles/understanding-biofilm
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287027/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521364/
It's pretty simple, if the disease is able to enter the form where it starts producing biofilms it can use them to evade antibiotics. A patient then must explore treatments to break up biofilms, and eradicate whatever infections or co-infections are present within them. There's medications that do this and more functional methods such as hyperbaric oxygen chambers.
The people who have symptoms after antibiotic treatment and the people who relapse after antibiotic treatment still likely contain Lyme disease biofilms and persister cells which are capable of causing a full relapse given enough time and the right conditions.
Those who receive early treatment and success with a single round of antibiotics are the lucky ones, and not the standard patient experience.
Even people who have been bitten by a tick, immediately started antibiotics, and caught it immediately can still get chronic Lyme disease, especially if their initial round of antibiotics was for too short a duration.
There is a lot of shit on the Internet, and what's happening to the people who have Lyme disease is an absolute travesty and crime against humanity due to our corrupt and failing medical system. The actually science and research on this is clear though: biofilms exist, Lyme disease can become chronic due to biofilms and persister cells which can evade antibiotics.
Everyone talks about how theres super bugs and infections that evade antibiotics, well Lyme disease is literally a super bug that evades antibiotics and is probably one of the most successful super bugs of our lifetimes and yet people try to deny its capabilities despite countless medical research studies proving otherwise. It's baffling really.