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Comment by ISL | Hacker News Reader

I've not met a professional that doesn't make internet searches for information when necessary.

I'm a professional physicist, and I search for specialty-specific information multiple times per day, every day.

Are there websites like StackOverflow where you find pharmaceutical receipes for acetylcysteine?

I think the parent is a physicist, not a pharmacologist, but I'm curious about what exists in both physics and pharmacology so I hope people chime in on both.

Physicist here. ENSDF (Evaluated Nuclear Structure Data File) is a fantastic resource for anything related to nuclear physics.

Person doing simulations in plasma physics / astro physics here. I google tons of stuff every day. And I have a hard copy of https://www.nrl.navy.mil/ppd/content/nrl-plasma-formulary on my desk. And the PDF on just about any of my devices. Once every few years I ask the Navy for 20 copies and hand them out to grad students and colleagues.

The Decay Chain article on Wikipedia is a go-to favorite of mine: https://en.wikipedia.org/wiki/Decay_chain

The graphics for the natural decay chains are eminently-usable and teachable.

Not a medicinal chemist, but I think the general procedure for that is to do a google (or better, Google Scholar) search for "$chemicalName synthesis".

Here you go:

One-step synthesis of N-acetylcysteine and glutathione derivatives using the Ugi reaction

https://www.sciencedirect.com/science/article/abs/pii/S00404...

I can't seem to find an openly available PDF, but you can search sci-hub to pirate that.

From reading the abstract and the graphics, it doesn't exactly look like something you cook up in the kitchen. For instance they run the reaction in trifluoroethanol, which is flammable, toxic, irritant and possibly causes reduced fertility from exposure.

Not sure if you have access to it, but reaxsys[1] is an amazing database for stuff like this. I've used it many times for looking for (un)safe reaction paths for particular drugs. It looks like the ``free'' version might let you get a lot of information from it.

Also, pubchem[2] might be of help as well. This is entirely free.

[1]https://www.reaxys.com/ [2]https://pubchem.ncbi.nlm.nih.gov/

That's usually done by literature search, which nowadays, can be done online. You draw a structure and it will look up literature that reported that as a product.

I haven't seen a website like stack overflow in the sense of posting questions like "How do I purify after this Beckmann rearrangement?"

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