Ask HN: Safe places to buy a house in the US

If you want to buy a house within continental US, what would be the top safest places for the next say 50-100 years if we ignore anthropogenic (social, economic) factors and focus only on geological, climatic changes, natural disasters, etc.

It's seems logical to assume that coastal states wouldn't be safe - some parts of the East coast most likely will be flooded, and there's too much seismic activity, drought and wildfires in the West.

So where do you think it would be safe?