I hadn't seen that before, but I don't think it addresses my biggest problem with HA automations: it's not a GUI.

When I'm developing my automations I often need to do a lot of testing and debugging when things don't work as expected. I find that Node-RED allows me to do this extremely easily as I can click on nodes and see what values are being passed around, and what state things are in.

Nonetheless, I'll look into AppDaemon :)