I like having a large, flat surface, without a bunch of clutter on the desk. It's important to make sure the desk and chair fit well together, such that your elbows and arms can rest on the table without stress. I use the Apple Magic keyboard and trackpad which lay flat on the desk, making it easy to get a comfortable position with minimal stress. Having limited clutter means I can easily move the mouse/keyboard around, switch between sitting and standing positions, and stay in a comfortable position. Additionally, I use an adjustable arm for my iMac which does not occupy desk space.

My standing desk: https://www.fully.com/jarvis-adjustable-height-desk-bamboo.h...

My adjustable chair: https://www.hermanmiller.com/products/seating/office-chairs/...

My adjustable monitor arm: https://www.fully.com/accessories/monitor-arms/esi-edge-max....