Performance is brutal though. For a moderately sized db client side datascript can be 100ms per interesting query unless you drop to indices. Might as well just do a server trip.
I had a beautiful dream of just streaming datomic out to datascriot but eventually gave up and went back to client side maps using reframe.
If Cognitect would release a performant JavaScript peer that would be a game changer for web dev. Just one db and effortless event streaming to and fro.