What about amarok? ( http://amarok.kde.org/ )I find iTunes to be terribly annoying and slow. I also don't have an iPod so... Do you run rockbox on it? ( http://www.rockbox.org/ )

I've found digikam ( http://www.digikam.org/ ) to work pretty well. Never really cared for iPhoto though.

Keynote, again never really used it. I hear it's much nicer than the MS equivalent.

The wife likes GarageBand and it does seem to be a pretty sweet app. Not really sorta thing so I don't really know of any replacement for it. Audacity is the only thing that comes to mind and it's not exactly the same kinna thing.