legalization doesn't have to mean that you can just walk into CVS and buy any drug you want, and it certainly doesn't have to mean that your doctor can recommend unapproved drugs to you.

legalization is compatible with certain reasonable constraints. advertisement of any drug (maybe even FDA approved) can be prohibited. sale of unapproved drugs can be restricted to certain specialty stores so there's no risk of people assuming it's safe just because it's at their pharmacy or grocery store. you can mandate warnings on the packaging and/or at the entrance to the store. you can say no such stores within x feet of a school.