Edit: I'm not a molecular biologist. Let's edit this to say "If someone has ingested alcohol and it's not yet metabolized to the extent that it is unable to create a discernable impairment I don't want them driving."
Edit 2: It sounds like an objective test for reflexes and response time would be a better test of impairment (of any type) rather than using blood/breath alcohol measurements as a proxy for impairment.