I've been using Restic recently for backups online (to Backblaze, which it natively supports) after using Duplicity for a while. I'm really, really impressed so far; the hash-based deduplication means:

- I don't have to think about deduplicating my own data, which works well with my packrat tendencies (e.g., multiple copies of music library on snapshots of old laptops);

- Full-disk backups of multiple machines will share a lot of storage (all system files from my desktop and laptop, both running the same Linux distro);

- Restarting a long upload doesn't depend on some finicky state regarding an interrupted previous backup; it can just rescan the whole disk and skip uploading blobs that are already there, which feels much more robust to me.