There's hope. If you look at the GUI for Figma (an Illustrator and Sketch vector drawing competitor), they've built it using the Canvas tag...and it works AMAZINGLY well. I don't know how they did it, but it feels more like butter than Sketch, and I love Sketch. I'm waiting for someone to come along and basically build the Flash equivalent of a canvas tag renderer. But it's going to take some serious smarts.
There is some precedence. Rich Harris (of Rollup & Svelte fame) has been toying with the idea of a precompiler for Web GL...