Especially if you have 4K monitors or a 3K/4K mix where the monitors need a different DPI set.
PopOS uses a system to manage the scaling very well. https://support.system76.com/articles/hidpi-multi-monitor/
The closest comparison I've seen elsewhere is fractional scaling in Gnome 3.32+: https://wiki.gnome.org/Initiatives/FracionalScaling
If you have a configuration / workflow for HiDPI on Linux, it'd be nice to see if there were other options / any other things out there.