To whomever downvoted this, DVT is absolutely a real thing and absolutely life threatening. Your heart doesn't have the pumping capacity to pump blood out of your lower legs so your body is designed to use calf muscle expansion and contraction to move the blood. If you sit idle for many hours the blood pools in your lower legs and your chance of a quite literally life threatening blood clot skyrockets. If you develop such a clot and get on anti clotting meds in time you'll probably be on them for the rest of your life. Voice of experience here. Getting up and walking around on a long flight is a really good idea. Can also happen to those who camp out in a chair without moving for 8 hour gaming or coding sessions.