There are many places throughout the south, midwest and northeast with decent job markets and dirt cheap housing. The mortgage on my 1800 sq foot house is nearly a third of the cost of my tiny one bedroom back in Seattle. The cost of the entire house is a tenth of a house in the Bay Area.
I am fortunate to work remotely but when deciding where to live I wanted to be able to afford to keep this roof over my families' head even if I didn't have a Bay Area/Seattle gig. I think the biggest obstacle may be coming up with enough cash to secure the financing in the first place, and for that I am grateful to have lived and worked in a tech hub.