A maybe minor point: It's more or less impossible to become a Swiss if you aren't already whereas it's kind of possible to become an American. If your company makes it it's entirely possible this can become a problem down the line, for instance regarding your tax status or rights and obligations.

Also, the culture is remarkably different, so if you're expecting something similar to the american college campus-like experience large companies offer over there you're in for a hell of a culture shock.