It currently doesn't do fully hermetic configurations (as in, where it is impossible for any inputs to come outside of the project). Instead build2 does high-fidelity builds where it makes sure that if any of the inputs change (including options, environment, compiler itself, etc), the target gets rebuilt. See my reply to a sibling comment for some details. We do plan to add support for hermetic builds though it won't be exactly like Bazel's -- the idea is to prevent and, where not possible, detect external changes and fail rather than rebuilding.

Regarding caching (and distributed compilation), this is currently on the TODO list though a lot of the infrastructure is already there. For example, the same change detection that is used for high-fidelity builds will be used to decide if what's in the cache is usable in any particular build.

While I agree we should mention these points in the documentation (things are still WIP on that front), I don't think cross-compilation deserves mentioning: for any modern build system it should just work. In build2 we simply implement things in the "cross-compile first" way, with native compilation being a special case (host == target).