My point here is that you can never say never, its not a matter of belief its a matter of the future being unpredictable.
Note that some physics predicts loopholes, but it isn't clear if they are real loopholes or places where out model isn't right in some detail.
I understand its inconceivable that something can exist that we haven't predicted with our current understanding of physics but we also need to realise that scientists 150 years ago thought the stuff we understand and use daily today were also inconceivable. I am talking about breakthroughs that may arise and after a few decades we'll be looking back and thinking how blind we are not to see them earlier. It happened before it may happen again.
Ever heard that faster than sound was impossible?
Ever heard splitting of atom was impossible?
I understand that I might sound dreamy but here is the thing it's far better to believe, try and fail than to never believe.