It's a bit of a ramble, but it's hardly incoherent. What seem to like diverse topics to a physicist are actually not all that diverse when looking from a holistic perspective. It's not that scientists are sitting on huge piles of data and mining them for interesting results without testing hypotheses (though we are doing exactly this in many domains), it's that the fundemental approach to statistical analysis is flawed.

With enough data, good enough filters, and a wide selection of adjustments for background processes, any model can be made to work. Putting the blocks together is fundementally an excercise in bias, and truly limiting this bias requires significant discipline that is highly disincentivized and therefore uncommon.

The way she writes invites dismissal from working scientists due to its imprecise and conversational style, but I think she makes many salient points about the flaws in the modern scientific institution.