Just for fun, for more perspective on big data, a human body generates around 1-10M new cells per second, and a cell contains about 10-100GB of information. So a single human is generating 1-100PB/s of data just in the new cells! (Give or take a few OOM)
OTOH the amount of "information" needed to perfectly simulate a cell is probably unbounded. Just a corollary of the fact that we currently don't know how to perfectly simulate reality. Even a single "real" number can take up infinite space.
This is a very good point. The 'information' in a cell isn't the base pairs in its DNA, but all the atoms that make up the whole cell. And then each atom encapsulates properties such as position, velocity, charge, van der Waals radius etc.
However this considers atoms with classical mechanics. In a quantum mechanical representation it would be very different again and you can start asking really hairy questions about whether information can be created or destroyed.
No storage system can store that data (and most of it is not useful) so they have a series of hardware triggers and buffers that reduce the data down to roughly what modern (general purpose) hardware is capable of handling. They tune the thresholds to match what consumer hardware is capable of.
With regard to supercomputer filesystems: nobody wants to use GPFS. CERN's EOS sustained (theoretical) 3.3TB/sec in Apr 2015, so it's not like they're uncompetitive with the largest supercomputer...
Obviously some people do want GPFS, if they can afford it, but Cori uses Lustre. I don't mean to claim that either is ideal for streaming high rate event data, of course.
Data model at CERN does not match the one of a supercomputer. CERN data are not processed locally but distributed and spread to ~100 of participating institute in the experiment.
Moreover, "personal opinion", GPFS is crap. It's an old relic from the 90s that has so many quirk and problem of design that it would deserves an entire conference on it. Plus the fact it's proprietary and expensive.
The only reason that make GPFS still alive is that for a long time, the only alternative was Lustre, and Lustre is even worst.
Every single supercomputer meeting I've been to (I've been part of the community for years, they often invite me to their meetings to give an industry perspective), people are just continuously complaining about the filesystems, and it's GPFS and Lustre at the top of the list.