AFAICT, assuming things keep progressing:
-- General purpose quantum computing is easily 8-10 years out: https://twitter.com/lmeyerov/status/1177632571636584448 . HW vendors might become lucrative around then, and soon after, SW. As a language & framework tool designer, I'll probably poke my head out again in a few years again.
-- Niche stuff, especially military, can be done over the next few years, with subsequent ROI in the 5-10 year range. Need funny secure radar tech with lossy analog circuits? Go for it!
-- Medium term: There may be some wins around say HFT doing probabilistic optimization algorithms on super lossy/unreliable quantum circuits, and maybe national label + pharma stuff for the same. This might be interesting for a larger-than-expected audience (breakthrough events for synthetic bio, genomics?), and as a tool designer, blaze the path to general SW, which is also interesting..