Inbreeding in a European ancestry sample from the contemporary UK population
nature.com
nature.com
I have heard (from unreliable sources) that consanguineous marriage is very common in parts of the Middle East, to the point that a male suitor must ask for and be granted permission by a woman's father's brother's sons before being allowed to marry her. This is known as "bint 'amm marriage"
This sort of arrangement - first cousins - has a relationship coefficient of 0.125 and is therefore under the threshold studied in TFA, and a quick search leads me to believe that it roughly doubles the chance of a serious birth defect. That said, given the strong cultural forces at work here I suspect that many of these unions are in fact between people who are multiply first cousins, which would magnify the effect.
Is anyone here familiar with any studies done on the genetic impact on communities where bint 'amm marriage is practiced?
For reference, here's the Wikipedia article on the practice: en.wikipedia.org/wiki/Cousin_marriage_in_the_Middle_East
Not great, but nothing world-ending.
They must surely have data on simple first cousins, but it didn't jump out at me.
For example, taking Fluid Intelligence Score (basically how smart you are), in Table 3, its extrapolated effect size is -3.43, so:
First cousin (relationship coefficient 0.125, inbreeding coefficient 0.0625) would give -0.214 to FIS. To put that in context, for medication, that would be considered a small effect size. So inbreeding at that level is a bit like taking a stupid pill.
Received wisdom is that a coefficient below 0.25 doesn't cause serious deleterious effect. I have no idea if that's well supported, but I imagine it's relevant to why it wasn't studied.
Many people don’t know who their biological parents are. While not a significant issue with adoption, if a guy has multiple kids who don’t know their siblings in the same area. Then they are likely geographically close and of similar ages...
This is enough to explain the contents of Arndale Centres, but even adjusted for the reasons they gave to believe it's too conservative, not enough to explain the Daily Express.
https://www.telegraph.co.uk/travel/news/the-most-googled-que...
I recall a story of a person who was refused gas at a rural gas station because they were not from the area. In a another town a motel refused Coast Guard workers a room because they weren't from the town.
Small towns can be weird.
In places that are not touristic or in smaller cities that are not a big metro areas, speaking German (Hochdeutsch) is not enough. Failure to speak the local dialect of that region will get you ridiculed or even discriminated against. Not just in the service industry, but in job hunting as well.
Also, don't be named Kevin.
It would be interesting to know more details about this 0.03 percent. No idea whether you should put your money on small towns or on big cities (e.g. parents both adopted & didn't know).
Why would people who lived in the town want a hotel room in the same town? How did they ever get any customers?
I got the story directly from my father who worked with the guys. It could have been bigotry maybe the men refused service were denied due to their appearance, accent, job (fishermen upset with Coast Guard workers).
My aunt was refused a hotel room in Quebec City because she is English. Her French husband asked and was told sure no problem but the clerk said to him in French "let me get rid of this English pig fisrt". My aunt spoke French ( awkward!). That was a story often told at family reunions.
That happened to me once. In Mingo County, West Virginia. With New York license plates.
This is the UK. There aren't any long distances ;-)