Last night's Rams/Seahawks game had a perfect example of this. A late-game pass from Jared Goff was tipped by the intended receiver and hit the ground behind him. The Seahawks' safety picked it up right away but the play was whistled dead (incomplete pass).
Except that's not what happened. To the refs on the field and to us at home, it looked like the ball hit ground. But a slow motion video replay showed that the safety never allowed the ball to touch the turf. He intercepted it.
This was a huge turn of events, and probably changed the outcome of the game. It wasn't borderline or vague. It was just too fast and the distances (between ball and grass) were too small to rely on a real-time judging of the result.