That's certainly one thing it should be about. Whether it is appropriate for the government to decide what substances people are permitted to introduce in to their own bodies is an important question though.
Thus it seems the only way to quell the social damage of drug use of for the government to not only decriminalize everything, but to also ensure drugs are given away by community centers with specialized staff.
Alcohol was pretty unsafe during prohibition, often containing methanol, a toxin which can blind or kill. Legalizing it meant that anyone producing and selling impure, mislabeled or adulterated alcohol could be sued or jailed. The same could be done with other drugs.