(Before someone does the inevitable HN calculation about why the materials used to make the Remarkable are far worse for the planet than all the trees killed to print grants - yes, you're probably right. YMMV.)
I had tried the various ipad and equivalents, and the RM's big advantage is that it feels like reading/writing on paper, mostly - something about the matte screen and stylus, though the stylus is sort of craptastic.
As others note, the software is clunky with annotations moving around on the page, and there's a bit of lag. But, I have yet to find anything better. I do wish there were an easy way to collect all the annotations in one place, but my handwriting as an MD is appallingly bad so that may be an impossible task.