Current ublock origin.
Your adblocker frequently updates lists of patterns to block via any of many user configurable lists.
When you load a site ON YOUR COMPUTER it consults all those lists including custom ones you create yourself for annoying elements on particular sites before loading content. It NEVER sends said content to the adblocker or leaks your information.
Ublock origin provides both the adblocking engine and the lists and can innovate on the former and iterate on the latter as fast as you please.
New chrome restrictions.
Google provides an adblocking engine substantially inferior to ublock. Extensions are able to provide only a list much smaller than current lists and can only update that list when the extension itself is updated. They cannot innovate on the adblocking engine as they are stuck with the crummy one an ad company provides. This basically ensures that ad providers win the arms race with adblockers.
Safari
Shares the same inherent flaw with chrome that Apple will be providing the adblocking engine with the possible benefit that apple isn't directly making money off ads and has less incentive to directly break adblocking.