Most of my software is written in Haskell, with the Yesod framework handling all the HTTP stuff. Data is mostly persisted in PostgreSQL, with some caching and queueing stuff done in Redis. I try to avoid JavaScript if I can help it. When I do need a richer UI, I'll add small bits of plain JavaScript, sometimes with jQuery. When I need a more complex UI, I use Elm. Everything runs on NixOS machines on AWS.
Not wrestling with constant runtime errors and not being afraid to make broad sweeping changes means I can adapt the software to the business more quickly.