The fake bus stop hack
telegraph.co.uk
telegraph.co.uk
http://www.webmd.com/alzheimers/news/20050105/curry-spice-ma...
I've known three people so far with Alzheimer's: My grandmother, my grandfather, and my mother-in-law.
My observation is that Alzheimer's definitely shifts your personality, but which direction it goes in is not obvious. My grandma ended up paranoid and distrustful. My grandfather remained cheerful and smiling right up to the end. (Neither of them actually died of Alzheimer's.) My mother-in-law is also fairly far over toward the good-cheer side.
It is tempting to observe that Alzheimer's tends to exaggerate an existing aspect of your personality: My grandmother was always paranoid and became more so; my grandfather was always fairly cheerful and outgoing. But some of that may be due to environmental factors: an Alzheimer's patient surrounded by familiar, friendly people and things is naturally likely to be happier. When you've got Alzheimer's, the influence of environment gets larger and larger, since it's your only possible source of continuity. That's what this awesome bus stop hack is exploiting.
#1. Keep your mind active as much as possible. Waste time by working puzzles instead of reading People magazine. Constantly learn new things whether they're useful or not, both inside and outside your domain of expertise. This approach has the most proven benefits and no known drawbacks.
#2. Lean toward a Mediterranean diet and drink a glass of red wine every evening. I don't think there's any need to be anal about it, but just avoid Atkins-like diets, take the fish option if one is available, etc.
#3. Stay physically active as much as possible. If you live in a walkable neighborhood, you're halfway there with no effort.
#4. Drink up to a cup of coffee a day. Also strongly implicated in improving prostate and kidney health, but may have cardiovascular disadvantages.
#5. Take B vitamins. I started with the widely-available "B-50" complex and moved up to "B-100" with an additional folate supplement to get to a total of 200% US RDA of folate. Evidence is sketchy about long-term benefits, but I find the effect to be similar to a cup of coffee without the crash or the jitters, so I'm sticking with it for that reason alone.
In a less interventional medicine system, my elder relatives would have been diagnosed "old age" instead of some obscure illness and left to themselves to die earlier (oh horrors!), sparing everyone and themselves from the tragedy of the mind dying and the body not dying.
Given that my mom has been showing signs of this for the past few months I'd be curious if anyone here actually knows more.
I've found "The 36-Hour Day" http://www.amazon.com/36-Hour-Day-Alzheimer-Dementing-Illnes... to be somewhat helpful so far. Anyone have any other good recommendations?
It seems to make all symptoms disappear within minutes - undergoing large scale testing now. Should be approved for Alzheimers within a few years.
Apparently it's difficult to tell the difference between Alzheimer's and vascular dementia while the patient is still alive -- examining a sample of brain tissue is the definitive test. I think I heard that the misdiagnosis rate is something like 50% (unreliable number, don't take my word for it). It doesn't make much sense for an anti-inflammatory drug to clear the protein plaques or undo neurological damage in the case of Alzheimer's disease, but it does make sense for the drug to improve blood flow to the brain for patients who actually have vascular dementia instead. So, perhaps there was a mix of patients in the (small) initial trials we've seen for etanercept as an Alzheimer's treatment that accounts for the surprising result.
Franz-Josef Goebel? Sounds suspicious.
On the other hand, here's a picture: http://www.alte-loewen.de/dpa2g.jpg