Many people kill themselves over chronic untreated or undertreated pain. I've seen studies showing that people with chronic pain kill themselves at twice the rate of those without chronic pain (even that seems low to me) [0] and various other similar studies. Assuming this is true, and that the two are causally related, then opiate deaths and suicide deaths due to chronic pain are in the same order of magnitude.
If you any of you are unfortunate to end up with a condition that causes significant chronic nerve pain, you'll quickly understand how this can be.
0. https://annals.org/aim/fullarticle/2702061/chronic-pain-amon...