Ask HN: Good MOOC/course on computer software/hardware performance engineering?
Think caches, hardware acceleration, SIMD, parallelism, etc.
You can also try searching for classes entitled "Advanced Computer Architecture" like so:
http://www.sci.tamucc.edu/~sking/Courses/COSC5351/syllabus.p...
I'd also check out Berkeley's FireSim tutorials and community
Best of luck! There is no down side to mastery of these dark arts ;)
[1] https://www.udacity.com/course/high-performance-computer-arc...
[2] https://www.udacity.com/course/high-performance-computing--u...