Here's the flip side: if no one else was interested in your area, it's probably not very interesting. Dropbox wasn't the first file-syncing service. Vimeo was started before YouTube. And there were plenty of social networks before Facebook, which was entering an area where there were large and well-funded incumbents when it was literally some kid's dormroom project.
It may be worth keeping in mind Fred Wilson's advice: once you're pretty sure you know what you want to do, put your head down and execute: http://www.avc.com/a_vc/2010/11/your-worst-enemy-is-yourself...