I've recently built a web app with Node and the time we spent solving problems which have already been solved a thousand times is astonishing. Things like picking an ORM, having a proper database migration system, running a test suite. It's actually quite depressing when you come from Rails where everything is working coherently out of the box.
The fact that there is no standards in the Node ecosystem make it a bit more painful. You have to carefully choose between many different libraries to solve your problem. Some of them are in TypeScript, other still use callbacks, etc. We basically had to glue together many libraries to get something working. All those hours could have been spent building the actual product and delivering value to our customers.
Hope they will ship many more releases!