Try Wipr, it's super simple and minimal and it works very well, but it costs $2.
If you want something free with more customization options (and open source) there's Adguard
I was using uBlock Origin until the move to the App Store (Mojave).
1blocker works well enough ever since then that I had to look it up on my laptop. Also available on iOS but I use Purify there.
With how good reader view is on both Safari and Firefox, I tend to rely on the ad-blocker less and simply use reader view when the page is finished rendering.