All the fancy keyboard make no difference if you type too much. Pre RSI I'd type out some code, consider it carefully, rewrite it, reconsider and rewrite. Only then would it be run. It multiplied up the amount of typing I'd do. Now I'll think it through before putting hand on keyboard. No experience with dvorak but logically less typing must beat a 'better' layout.
Emails are shorter now. Just practice getting to the point. Writing docs, I used the dragon voice recognition. It works acceptably when trained, though that is not a quick and painless process.
I have a kinesis keyboard and its splitting/tilting don't help. But, because it lacks a number pad to the right it means I can place my trackball closer, so less risk of shoulder stress from reaching further out sideways. That's very worth it.
I found a mouse to be bad, something to do with pressing the button on top. I now use a trackball. I suspect that's specific to me though.
Above all, when it starts hurting, stop, and for a decent period of time - "But I can't afford to stop!" will be your response. Well, you will stop, nolens volens, it'll just be whether you choose to or your body packing up.
Hand RSI is really bad, I have it now and it'll never go away. It gets better but it's taken over a decade and I'll have it forever. So please note my the para about it hurts so stop.
Also be really cautious about any device that claims to help RSI such as those gyroscopic hand exercisers. They can help when it's improved (IME anyway), but when it's bad it will aggravate it.
All the above my own experience, with a grain of salt as everyone's different - except for the bit about "when it starts hurting, stop" cos I think that's probably universal.