We have understanding of gravity, as Newton's laws explain the behaviour of everything that falls to anything else. That's compression: You don't need a long list of measurements of falling things, you just need a much shorter list of starting conditions. Newtons laws will then decompress the long list of measurements from it.
So what does it mean for protein folding? We need more compression so the knowledge is understandable on the human scale? Or AI needs less compression, so it is reasoning in a better way for this problem. Isn't that just a more abstract way for saying AI is smarter than we are.