My wonder is why it shouldn't be powered by the sugar in the blood just like every other organ. That's where a real miracle will lie. I understand issues with coagulation on silicon parts.
(There are probably a whole host of knock on effects that I'm not considering. I'm not a biologist.)
We could follow traditional glycolysis but without a recapture method, would cells create excess ATP? What would that affect? Would it change the production of insulin and it’s affects on storing tryglicerides? I barely have enough knowledge here to ask questions let alone have answers.
Anyway, I'm not sure breaking glucose is that useful. Won't it just make people hungry?