Then, out of nowhere, some 'interesting' stuff happens. It'll all be in that one chunk,which will get hammered during reads.
Like, imagine all the telemetry data and video that was taken during a single moon landing. Most of the data made into a time series is from the days in transit. 99% of it will be "uninteresting." But the moment Neil Armstrong puts his feet on the Moon surface, and the moments leading up to and subsequent of that event, will be the "hot chunk."
Advice: Take Zipfian distributions into account for data access.
(Disclosure: I work at ScyllaDB, which scales horizontally and vertically, and we work under various open-source time series databases like KairosDB and OpenNMS' Newts. Not trying to knock them, but hopefully save them from worlds of hurt found out the hard way.)