But someone who does not understand the employee's autism might leave satisfied with why the employee would not like to complete the task, but assume that the initial blunt "no" was deliberate disrespect or disregard for the manager's request... and after a series of interactions like this, come to an erroneous conclusion that the employee desired to be uncooperative or doesn't care about showing any regard for our feelings.
Understanding why helps us be empathetic and "not take it personally."