You have Django and DRF and Flask. DRF is, by far, the best designed framework for building APIs in any programming language I have ever seen, and I've at this game for a long time.
JavaScript has 10 times more packages than PyPi, and for the most part they are absolute garbage with no intent on being maintained.
Python has substantially fewer packages where the community rallies around them and keeps them as best-in-class. SQLAlchemy, DRF, factoryboy, requests, etc., are all incredible one-stop-shops for the vast majority of use cases.
You don't need 15 libraries for doing HTTP requests. You just need one good one that does the job so you never have to think about the problem ever again. Python excels at this class of libraries and by comparison npm has appalling choices.