Life and self awareness is great argument against this theory. But it looks like some dudes get offended by arguments like that for some (known) reason :). Actually the critical part of life in simulation argument is the First person perspective of conscious living things such as ... yourself. Simulation in our world is mathematical mocking of some physical laws, it works on information level, so it's not creating anything. The moment you say that a simulation created life/self aware beings you are not talking about simulation anymore. You're just talking about different creation theory which looks like a simulation except that it's not working with simulated objects but very real things and it doesn't matter here what you call this. I hope that people understand that self-awareness is strong enough argument that's capable of debunking many nonsense theories (simulation, illusion of freewill...).