Ask HN: What are micro problems in Biotech?

I'm new to HN and I loved the idea that there are so many hackers over here. Enough with the thanks, I really want to know how the biotech industry is going. What I see on the internet, and the book "Zero to One", it's pretty much way opposite to the tech industry. There are huge problems like anti-aging, curing cancer, genetic diseases, and etc. But are there any problems in the lab? Like any reason why the experiments can be slow, hard to reverse engineer biology, and etc. I know this question is pretty vague and hard to understand, but I hope to find some discussions about the problems in biotech.