Money quote, at about 15:20:

"The very attributes of Ruby that I find distasteful are what give rise to all the wonderful software that the Python world can never have. And vice versa -- the very thing that makes Python aesthetically pleasing to me is exactly what leads to not being able to do any of this cool stuff. Ever."

This is after complaining about how complicated Ruby syntax is, but then showing how RSpec uses that malleable syntax to make what he considers to be beautiful code.