But I completely agree that a world without human agency wouldn't mean it would be a dead world. It could be bustling with activity, but the individual agents could still be very repressed or outright empty, automatons if you will.
When I speculate about such extreme extrapolations, the one ray of hope I have is that we might colonize the galaxy, and something could gets away, by accident, be it people or just organic matter. But until then it could be a very long and very dark stretch.
Of course, that's assuming the universe isn't teeming with life anyway, in which case I don't think even the supermegaborg could conquer all of it. I'm just worried about our place in it, if we get to experience it or not, how and as who. FWIW I genuinely am, it's not just as a hyperbolic argument against mass surveillance (in combination with automation and military robotics, I would add).