Take the example of the Android ecosystem: If plugins were allowed for apps, pretty sure there'd be a better story around privacy today. An astonishing 40% of connections from an Oppo/Vivo or Xiaomi phones are to ad networks and trackers. And there's nothing you could do (without root) except to firewall it (apps have started working around pi-hole esque setups). XposedMod has brought plugin based development to Android [2], but it is niche and requires not just root, but replacing key framework components. Using it might still be worth it, though, given the relentlessness of OEMs and carriers.
And that's just sad.
[0] One way to tackle the problem of developers selling away rights to their extensions is to legally make it binding to publicly declare whenever ownership changes hands. Disable extensions across all installs, and let the users enable after the fact is made obvious to them.
[1] https://www.eff.org/deeplinks/2019/06/adversarial-interopera...