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Comment by hellofunk | Hacker News Reader

It would be great to know if there were obvious lifestyle or diet changes that can help the natural mechanisms at work in possibly removing these cells.

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It’s hypothesized that intermittent fasting is a natural mechanism. This article is a good introduction: https://lifeapps.io/fasting/a-beginners-guide-to-intermitten...

I would warn that the studies on that are still preliminary. Even really promising research, like the Vitamin D supplement craze from a couple of years ago, can fizzle out when more data comes in.

There are... autophagy.

Cannibalizes any under-performing cells.

Autophagy is the self-cannibalisation of cells to give up their molecular components. Are senescent cells capable of doing this? They have at least stopped producing nucleotides, and the double nucleus suggests they have broken down toward the end of mitosis.

Senescent cells can be cannibalized by others. One method involves a feedback system in NRF2 via the modulation of p62. NRF2 activates the expression of many autophagy genes, such as Atg3, Atg5, Atg7 and SQSTM1 during cellular stress response. One component I have been self experimenting with to induce the up-regulation of NRF2 is Sulforaphane. Thus far I have removed cells in my body that were causing eczema.

Disclaimer: I am not a scientist and nobody should self experiment. I simply reached a dead end with doctors and won't accept "nothing can be done" as a valid answer.

A lot of research suggests that fasting does exactly that

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