You can think of it like the four color theorem. A beautiful theoretical result (though a far less beautiful proof), but the only practical significance is now cartographers know they'll never need that extra crayon....
If I interpret this correctly it's a tighter bound than the original conjecture, so it should allow better optimizations.
Apparently, for ISA with a small number of registers, graph-coloring is not as relevant because spillover is more important.
https://lists.llvm.org/pipermail/llvm-dev/2017-December/1199...
Most importantly, though, Huang’s result lays to rest nagging worries about whether sensitivity might be some strange outlier in the world of complexity measures, Servedio said. “I think a lot of people slept easier that night, after hearing about this.”
I'll have to reread the paper a couple more times, but I think Boolean sensitivity could be related to the security one has around any given need. There may be further implications around how to assess one's strategies for meeting needs, as those would be the individual inputs to the Boolean function of "Is the need for _____ security met?" This could help provide a theoretical framework for designing systems oriented around well-being.