However, it far from the last 'unconquered' sector of the web. There will never be an end to vast opportunities on the internet, because new solutions create new opportunities that never existed before, ad infinitum.
For example, and idea like grubwith.us would have seemed bizarre before Groupon, but now it seems like a straightforward evolution (and something lots of people would like to do).
We still are working with very basic forms of artificial intelligence, but as it gets better, the whole internet will be reborn.
Carry on inventing everyone!