There are at least two currently-running candidates who do seem have the balls to directly confront the pharma industry! Why do you think there aren't?
And because big pharma seems to always win.
Pharma gets what they pay for. Vote for someone who isn't beholden to them.
Hell, because of the Electoral College, my vote ultimately doesn't count if it isn't what the whole state picks.
Hilary had some uncomfortable ties to Wall Street -- she was a Senator from NY, mind you -- and the DNC chair Debbie Wasserman-Schultz picked up a lot of Budweiser money by scrapping any DNC talk of Marijuana Legalization (DWS has long battle MJ Legalization in Florida, so she's been taking their money for a while, or was a sympathetic bribe for Alcohol). But I could have lived with that in exchange for working health care and sane foreign policy.
[1] see also: the russian firehose of propaganda -- https://www.rand.org/pubs/perspectives/PE198.html