This comes down to something akin to Einstein's problem with quantum physics, that it didn't make aesthetic sense to have something be fundamentally random. That it is the same, and philosophically preferable, to say that something is fixed, but cannot be measured, than to say it is actually random.
Now, I hear that with quantum stuff they somehow have proved it to be fundamentally random, but the point is that if you really can't tell in any way, the difference doesn't matter at all. At least to a reductionist viewpoint. I feel that philosophies about "what if reality is a simulation or a dream?" are dumb for the same reason. Unless there's a way to wake up, who cares?