For yet another study in ... mice.
There are other options like dogs and pigs which are much better models for human biology, so if you really want to make a claim about subtle effects of human genetics you need to be as close to a human model as possible.
This is entirely ignoring the someone generous leap they make that one single gene mutation is responsible for an increased rate of heart disease. It also doesn’t touch on what the benefits for that gene were (to spread through the gene pool completely it must have some benefit that outweighs the cost)